Timothy M Block Selected Research

ureido-N-hexyl deoxynojirimycin

1/2018	Enhancing the antiviral potency of ER α-glucosidase inhibitor IHVR-19029 against hemorrhagic fever viruses in vitro and in vivo.
2/2017	Ester Prodrugs of IHVR-19029 with Enhanced Oral Exposure and Prevention of Gastrointestinal Glucosidase Interaction.

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Timothy M Block Research Topics

Disease

45	Infections 01/2021 - 07/2002
24	Hepatocellular Carcinoma (Hepatoma) 02/2016 - 05/2003
15	Hepatitis B 01/2021 - 03/2004
14	Chronic Hepatitis B 07/2021 - 11/2006
13	Fibrosis (Cirrhosis) 01/2021 - 03/2005
11	Virus Diseases (Viral Diseases) 12/2016 - 11/2006
11	Neoplasms (Cancer) 02/2016 - 05/2004
9	Liver Diseases (Liver Disease) 01/2017 - 05/2003
7	Liver Neoplasms (Liver Cancer) 09/2015 - 01/2005
6	Colorectal Neoplasms (Colorectal Cancer) 03/2012 - 05/2004
5	Viremia 11/2016 - 01/2011
5	Diarrhea 04/2013 - 03/2002
5	Liver Cirrhosis (Hepatic Cirrhosis) 01/2012 - 01/2008
4	Hepatitis 01/2016 - 10/2004
3	Dengue (Dengue Fever) 01/2018 - 04/2013
3	Viral Hemorrhagic Fevers (Viral Hemorrhagic Fever) 01/2018 - 06/2013
3	Porcine Reproductive and Respiratory Syndrome (PRRS) 07/2014 - 01/2009
3	Melanoma (Melanoma, Malignant) 01/2009 - 02/2006
3	Adenomatous Polyps 08/2008 - 05/2004
2	Yellow Fever 01/2018 - 12/2016
2	Fever (Fevers) 01/2018 - 06/2013
2	Hepatitis C 01/2016 - 09/2015
2	Chronic Hepatitis C 09/2015 - 09/2002
2	Pheochromocytoma 10/2010 - 07/2002
2	West Nile Fever 07/2009 - 06/2006
2	Neoplasm Metastasis (Metastasis) 01/2008 - 02/2006
1	Ebola Hemorrhagic Fever 01/2018
1	Japanese Encephalitis 01/2018
1	Carcinogenesis 01/2018
1	Marburg Virus Disease 02/2017
1	Sclerosing Cholangitis 01/2017
1	Cholangiocarcinoma 01/2017
1	Body Weight (Weight, Body) 12/2016
1	Hepatitis A (Hepatitis, Infectious) 01/2016
1	Bites and Stings (Sting) 02/2015
1	Disease Susceptibility (Diathesis) 01/2015
1	Common Cold 05/2014
1	Arthritis (Polyarthritis) 12/2013
1	Joint Diseases (Joint Disease) 12/2013
1	Inflammatory Bowel Diseases (Inflammatory Bowel Disease) 12/2013
1	Crohn Disease (Crohn's Disease) 12/2013

Drug/Important Bio-Agent (IBA)

32	Antiviral Agents (Antivirals)IBA 01/2021 - 09/2002
21	Proteins (Proteins, Gene)FDA Link 01/2017 - 05/2003
20	Biomarkers (Surrogate Marker)IBA 01/2017 - 05/2003
12	DNA (Deoxyribonucleic Acid)IBA 11/2015 - 05/2004
9	Glycoproteins (Glycoprotein)IBA 01/2017 - 03/2002
9	CytokinesIBA 02/2015 - 12/2007
7	Interferon-alpha (Interferon Alfa)IBA 09/2015 - 12/2007
6	GlucosidasesIBA 01/2018 - 03/2002
6	Pharmaceutical PreparationsIBA 11/2016 - 08/2012
6	InterferonsIBA 02/2015 - 09/2002
5	Hepatitis B Surface Antigens (HBsAg)FDA Link 07/2021 - 03/2006
5	Pattern Recognition ReceptorsIBA 02/2015 - 01/2009
4	Immunoglobulin G (IgG)IBA 12/2013 - 01/2008
4	SugarsIBA 06/2013 - 04/2009
4	Viral DNAIBA 06/2013 - 12/2002
4	OligosaccharidesIBA 07/2011 - 01/2005
3	Surface Antigens (Surface Antigen)IBA 07/2021 - 01/2016
3	RNA (Ribonucleic Acid)IBA 01/2021 - 05/2003
3	VaccinesIBA 01/2021 - 01/2016
3	Toll-Like Receptors (Toll-Like Receptor)IBA 02/2015 - 01/2009
3	LectinsIBA 12/2013 - 02/2008
3	Galactose (Galactopyranose)FDA LinkGeneric 12/2013 - 02/2008
3	alpha-Fetoproteins (alpha-Fetoprotein)IBA 01/2013 - 06/2009
3	Nerve Growth Factor (NGF)IBA 08/2007 - 07/2002
3	Peptides (Polypeptides)IBA 03/2006 - 05/2003
2	Hepatitis B e AntigensIBA 01/2021 - 04/2012
2	ureido-N-hexyl deoxynojirimycinIBA 01/2018 - 02/2017
2	glucosidase IIBA 01/2018 - 01/2015
2	ProdrugsIBA 02/2017 - 09/2013
2	A-Form DNA (A-DNA)IBA 11/2015 - 01/2012
2	Interferon Type IIBA 07/2014 - 01/2012
2	AntibodiesIBA 12/2013 - 07/2008
2	Polysaccharides (Glycans)IBA 10/2013 - 02/2009
2	Imino SugarsIBA 06/2013 - 01/2011
2	Kininogens (Kininogen)IBA 01/2013 - 06/2009
2	hydrogen sulfite (bisulfite)IBA 01/2012 - 01/2011
2	Messenger RNA (mRNA)IBA 01/2012 - 05/2003
2	PhosphoproteinsIBA 01/2012 - 07/2011
2	AntigensIBA 07/2011 - 02/2008
2	ProteomeIBA 07/2011 - 05/2003
2	Interferon-gamma (Interferon, gamma)IBA 01/2011 - 09/2010
2	Ribavirin (Virazole)FDA LinkGeneric 01/2011 - 09/2002
2	Membrane Proteins (Integral Membrane Proteins)IBA 12/2010 - 08/2010
2	Serine Proteases (Serine Protease)IBA 01/2010 - 04/2008
2	Phosphotransferases (Kinase)IBA 09/2007 - 10/2002
2	NucleotidesIBA 01/2005 - 05/2004
2	Codon (Codons)IBA 01/2005 - 05/2004
1	benzamideIBA 01/2017
1	alpha-2-HS-GlycoproteinIBA 01/2017
1	BenzodiazepinesIBA 12/2016
1	Toll-Like Receptor AgonistsIBA 02/2015
1	vadimezanIBA 02/2015
1	ChemokinesIBA 02/2015
1	Immunologic Factors (Immunomodulators)IBA 12/2013
1	agalactosyl IGGIBA 12/2013
1	Tetracycline (Achromycin)FDA LinkGeneric 09/2013

Therapy/Procedure

20	Therapeutics 01/2021 - 09/2002
2	Oral Administration 12/2016 - 01/2011
1	Blood Transfusion (Blood Transfusions) 01/2016